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Oxidative stress was evidenced by the depletion of cysteine and the increased levels of cystine and methionine sulfoxide (Met-SO)

doi: 10.3389/fcimb.2021.657775 Received 24 January 2021 Accepted 11 May 2021 Published 03 June 2021 Volume 11 - 2021 Edited by Diego Luis Costa, University of So Paulo, Brazil Reviewed by Maria Regina DImprio Lima, University of So Paulo, Brazil

Excessive pro-inflammatory eicosanoids production contributes to sustained inflammation and increased ROS generation in ARDS patients (Figure 2)

Guilford, F.T

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In addition, H2O2 is involved in mediating biological processes, including PCD (Desikan et al., 1998), ABA-mediated stomatal closure (Pei et al., 2000), auxin-regulated gravitropic responses (Joo et al., 2001), mechanical wounding response (Orozco-Cardenas et al., 2001), systematically acquired resistance (SAR) (Inz and Van Montagu, 1995), plant pathogen interaction (Mittler et al., 1999), and some other processes relating to both biotic and abiotic stresses (Desikan et al., 2003)