Tirzepatide leads the pack for both weight loss and blood pressure reduction
It has a neuroendocrine pathway independent of the GLP-1 receptors, working by stimulating melanocortin-4 receptors (MC4R) to reduce hunger and increase basal metabolic rate
The hormone then signals to your brain to reduce appetite, tells your pancreas to release insulin, and slows gastric emptying (how fast food leaves your stomach)
A good probiotic, electrolytes, NAC, calcium D-glucarate, and TMG support gut, liver and brain health
The results will facilitate further studies on how GLP-1 regulates the sympathetic system and other autonomic and somatic functions via the spinal cord
doi: 10.1016/j.eclinm.2021.100979 99 GorelikYGhersinILujanRShlonDLoewenberg WeisbandYBen-TovAet al