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The five qualifying conditions The five qualifying conditions for the NHS pathway under NICE TA1026 are 4 : Type 2 diabetes High blood pressure (hypertension) Cardiovascular disease (previous heart attack, stroke, angina, or coronary procedure) High cholesterol or dyslipidaemia Obstructive sleep apnoea For the private route, the Mounjaro and Wegovy product licences accept any one of these, plus prediabetes (an HbA1c blood-sugar reading between 42 and 47 mmol/mol) 1,2

In STEP UP, the 7.2 mg dose produced an average weight loss of 20.7% over 72 weeks, compared with 17.5% on 2.4 mg, while going from no medication to 2.4 mg added far more than that

Identification of programmed cell death-related genes and diagnostic biomarkers in endometriosis using a machine learning and mendelian randomization approach

doi: 10.1002/jcp.29403 78

Treatment with GLP-3R was associated with improvements in several cardiometabolic risk factors

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