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It is important to follow the prescribed doses and directions from your provider accurately in order to minimize risk and/or severity of potential side effects

Cold medication might contribute to injection discomfort for some patients

In women , severe or prolonged calorie deficits can disrupt the hypothalamic-pituitary-ovarian axis

And then it's medication for life

The metabolism and clearance of both components may be affected by significant liver disease, and patients with severe hepatic impairment should be monitored closely if treatment is deemed necessary