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The original agreement has been successfully extended through December 31, 2026, to accommodate time required for PharmaCO's receipt and review of Lexaria's 2026 research & development ("R&D") results related to GLP-1

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In a commentary on the investment, Gilead chief executive Daniel O'Day said that the company already carries out most of its R&D within the US and has "been increasing our investment in US manufacturing over the last several years, with two large-scale cell therapy sites, and we have additional investment projects underway that are expected to run through 2028." Around $4 billion of the new tranche of funding is earmarked for capital projects, including labs and equipment, with another $5 billion aimed at "technology, operations, and R&D site activities." The remaining $2 billion will be spent on "digital and advanced engineering activities." Gilead expects to create around 800 new jobs from the new funding allocation, with another 2,200 in indirect positions like construction, by 2028

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For the time being, the proposed treatment algorithm for patients with DM2 and NAFLD/NASH focuses on caloric restriction, especially those acquired by ingestion of fructose and alcohol, and initiation of aerobic exercise, targeting an overall body-weight reduction of 710%

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