Primary Handling Editor: Karen OLeary, in collaboration with the Nature Medicine team
Dosing: Weekly subcutaneous injection Maximum dose: 15 mg/week Average weight loss (SURMOUNT-1): 20% over 72 weeks at the highest dose List price: ~$1,086/mo Self-pay: From $399/mo via LillyDirect FDA-approved for: Adults with BMI 30 (or 27 with comorbidities) Side-by-Side Comparison Side Effects: Similar, but Worth Reading Both medications have GLP-1-class side effects: nausea, diarrhea, vomiting, constipation, abdominal pain
H., Friedman J
Some struggle with nutrient absorption, distribution, metabolism, or excretion
What are these medications, and how do they work
Moreover, the percentage of mean changes scores were significantly different between the two groups in frailty status and hand grip test