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However, this does not mean the combination is without considerations

Retinopathy increases the risk for other diabetic eye problems that cause blurry eyesight and, potentially, vision loss

Additionally, wipe the rubber stopper on your medication vial with an alcohol swab before drawing your dose to maintain cleanliness

GLP-1 medications can cause mood changes in some patients

Tirzepatide is a synthetic dual incretin receptor agonist (molecular mass 4.8 kDa, water-soluble) that has recently emerged as a novel therapeutic strategy for metabolic disorders by targeting both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors (GLP-1R), leading to marked improvements in glycemic control and body weight in clinical trials for T2DM [4] (Table 1, Figure 1)

Tirzepatide's prescribing information includes a boxed warning regarding thyroid C-cell tumors, based on rodent studies showing dose-dependent and treatment-duration-dependent increases in thyroid C-cell tumors