B12 has been popular among athletes for many years for its natural energy boosting effects but more recently there has been more awareness as to what more B12 can help with
I used some out-of-date ampoules last year but, more recently, happened to need blood tests so asked for B12/Folate to be checked
But since I never dropped back to the massive levels of fatigue I was previously feeling, I havent felt it was something to continue using since those ended
MOTS-c's AMPK activation is documented in Cell Metabolism

Chan School of Public Health: "Vitamin B12." Inflammatory Bowel Diseases: "Prevalence of and risk factors for vitamin B(12) deficiency in patients with Crohn's disease," "Vitamin B12 deficiency in inflammatory bowel disease: prevalence, risk factors, evaluation, and management." MedlinePlus: "Cyanocobalamin Injection." National Health Services: "Hydroxocobalamin," "Treatment -Vitamin B12 or folate deficiency anaemia Contents," "Vitamin B12." Nutrition Reviews: "How prevalent is vitamin B(12) deficiency among vegetarians?" Surgery for Obesity and Related Diseases: "Vitamin B12 deficiency in patients undergoing bariatric surgery: preventive strategies and key recommendations." The American Journal of Clinical Nutrition: "How common is vitamin B-12 deficiency?" The American Journal of Gastroenterology: "Vitamin B12 deficiency in untreated celiac disease." Top B12 Injections Who Get Them, How Quickly They Work Related Articles 22 Healthy Foods High in B VitaminsAny deficiency of B vitamins can lead to various health conditions

Dietary deficiency: Vegans (strict vegetarians who do not eat any meat, fish, egg, or dairy products) can develop vitamin B 12 deficiency because they lack vitamin B 12 in their diets