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Sleep begins with NREM sleep, subdivided into three stages: N1, N2, and N3

ClinicalTrials.gov lists early human research, including a Phase I safety and pharmacokinetic study and a more recent Phase II study involving acute hamstring injury

Decades of follow-up work turned it into one of the most studied peptides in cosmetic science

The same research group also published a study in older adults with HIV showing similar benefits, including reduced oxidative stress and improved mitochondrial fatty acid oxidation (Kumar et al., Antioxidants, 2020) [30]

Thus, PRP injections are hypothesized to expedite the reparative trajectory and enhance the regenerative potential across all zones of the meniscus