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Recognizing that a longer duration of known diabetes was associated with an increased risk of incident DR, we accounted for the duration of T2D by comparing the incidence of diabetic eye disease in individuals with GLP-1 RA prescriptions who had a diagnosis of T2D within less than 10 years vs greater than 10 years after the index event

Formulated in fast-dissolving sublingual tablets for fast absorptionwithout being inactivated by the liver

Tirzepatide: This is the active ingredient in Mounjaro and Zepbound

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36 , e3215 (2020)

The absence of pituitary stimulation changes its signaling profile compared to GH secretagogues