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Zhou NN, Ding FF, Wang T, Dong WX, Qiao F, Du ZY, et al

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Alongside promoting weight loss, GLP-1 receptor agonists deliver key therapeutic benefits for patients with type 2 diabetes

mTOR signaling factors downstream of IGF1R play key roles in the regulation of cancer cell metabolism, lipid and protein synthesis and they are responsible for several metabolic adaptations (Guertin and Sabatini, 2007)