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Following the device-specific Instructions for Use, which directs users to place the pen base flat against the skin, is the primary method to ensure subcutaneous delivery

Having worked with patients over 65 for nearly two decades, I find that slower dose escalation consistently produces better outcomes than rushing to maximum doses

B.CongL.et al (2021a)

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[123] underlines engagement, ethics, and representativenessconcerns we operationalise by quantifying annotation practice and agreement, documenting dataset biases, and proposing concrete reporting and linkage practices (e.g., consistent use of MedDRA coding) to translate social-media signals into pharmacovigilance workflows

& Pincus, M