10.3389/fendo.2019.00051 [DOI] [PMC free article] [PubMed] [Google Scholar] Mansur, S
Special Considerations 7.5.1
Lower doses still produce significant weight loss with better tolerability for many patients
An optimal metabolism can cure excessive tiredness, excessive coldness, and other neurologic problems like dizziness and headaches
Potential therapeutic effects (based on animal and early human data): Enhances tendon, ligament, and muscle repair Promotes angiogenesis (formation of new blood vessels) Reduces inflammation and oxidative stress Protects gut mucosa and may aid in GI disorders (ulcers, leaky gut) May support neurological recovery and joint health Modulates nitric oxide and dopamine/serotonin pathways (possible mood, focus benefits) (Note: Most data are from preclinical studies
The identification of these metabolites was based on MS/MS experiments performed in positive ionization mode