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H., Kim, K.-A

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While bacterial components such as bacterial lipopolysaccharide (LPS) are full agonists for TLRs, oxLDL components like POVPC often appear to act functionally as partial agonists of TLRs, so that activation of macrophages and dendritic cells by full agonists like LPS is reduced in the presence of oxLDL (353,354)

10.1136/jnnp.52.8.940

In this regard, mutations to NRF2 and its regulator KEAP1 have been found in cancer cells, supporting the supposition that antioxidant genes are pivotal in tumor progression 59,60,61,62