Because on GLP-1 therapy, the barrier to eating is already high
A long-standing hypothesis for why GLP-1 (and other gut peptides for that matter) are increased after RYGB is that the shorter length of small bowel leads to more rapid nutrient delivery further down into the GI tract where the majority of L-cells are located (62)
thus, it has a long half-life and strong biological activity
Lucke-Wold B, Seidel K, Udo R, Omalu B, Ornstein M, Nolan R et al (2017) Role of tau acetylation in Alzheimers disease and chronic traumatic encephalopathy: the way forward for successful treatment
Russald Medical Center is not affiliated with or endorsed by Novo Nordisk.) Is semaglutide for weight loss or type 2 diabetes
Experts recommend precision nutrition strategies: Smaller, nutrient-dense meals rich in high-quality protein Micronutrient support for vitamins B12, D, folate, magnesium and iron Hydration solutions to counter reduced thirst signals Fiber and probiotics to support gut health GLP-1 therapies are revolutionizing obesity and diabetes care, but they also reshape physiology in ways that demand attention