J Neurochem 64:27732782 Ebert D, Haller RG, Walton ME (2003) Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy
Summary: Some patients taking Wegovy report emotional changes such as mood swings, tearfulness, or low mood, though current UK regulatory evidence does not confirm a direct causal link between GLP-1 receptor agonists and mood disorders
CNS Spectr 12 : 5156 5961
NewsHealth Why cheaper alternatives to weight-loss drugs like Wegovy, Zepbound will be tougher to get The days of cheaper alternatives to popular weight-loss drugs like Wegovy and Zepbound are over for some Long Islanders and are numbered for others, pharmacists and compounding industry groups say
S1PR2, located both in the liver and in the brain, activates the ERK and AKT pathways that regulate cell survival, inflammation, and stress response in the CNS
Further, compared to insulin use, GLP-1RA use was associated with a significantly reduced risk of lymphoid leukemia, myeloid leukemia, MPN, MDS, amyloidosis, non-Hodgkin lymphoma, monoclonal gammopathy, and multiple myeloma