doi: 10.1016/j.lfs.2021.120274 27 EltayebKAlfieriRFumarolaCBonelliMGalettiMCavazzoniAet al
Overexpression of these growth factors is associated with glaucoma, as it disrupts ECM turnover, leading to excessive ECM accumulation in the AH outflow pathway, increasing outflow resistence and ultimately resulting in elevated IOP, which contributes to glaucoma development (83, 84)
Pelo is an evolutionarily conserved gene found in diverse species from archaebacteria to humans 18,19 and contains an RNA-binding domain similar to eukaryotic release factor I (eRF1) 20,21,22
1991 Aug;32(2):143-49
Slotkin TA, Vevin ED, Seidler FJ: Comparative developmental neurotoxicity of organophsphate insecticides: effects on brain development are separable from systemic toxicity
Intracameral delivery of layer-by-layer coated siRNA nanoparticles for glaucoma therapy