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Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via Dynamin-like protein

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However, in patients treated with diclofenac and glucocorticoids, the risk of peptic ulcer and gastrointestinal bleeding may increase, so special attention should be given in case of prolonged treatment, even in the absence of serious gastrointestinal symptoms

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Because nerves heal slowly, researchers often look at timelines of 4 to 12 weeks to see significant changes in nerve density

doi: 10.1097/AJP.0b013e3182a0e085