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Consistently, the daily supplementation of these -3 PUFAs was found to reduce or reverse the symptoms of DES in different species including humans [74,75,76]
Bioactive Compounds Omega-3s, medium-chain fats, berberine, curcumin, and capsaicin can enhance GLP-1 secretion or slow its breakdown by inhibiting DPP-4 the same enzyme targeted by DPP-4 inhibitor drugs
(The recommended dose for hypothyroidism in the 2016 study referenced earlier was 1800 mg per day
Examples include salmon, tuna, and shrimp
Additionally, literature has reported that ALA can inhibit RANKL-induced osteoclastogenesis via the FFAR4/arr2 signaling pathway and prevent inflammation, which is consistent with the findings of this study [37]
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