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BenjaminiHochberg false-discovery rate corrections (set to 5%) were applied to the results with and without outliers individually

The REDEFINE 1 and 2 trials evaluated the effects of cagrilintide 2.4 mg and semaglutide 2.4 mg on weight loss in patients with overweight or obesity, with and without type 2 diabetes

This compounds across multiple exposures, which is why strict cold chain discipline matters from the moment of reconstitution

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On February 27, 2026, the newly appointed Department of Health and Human Services (HHS) Secretary, Robert F