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Indications * Gastroesophageal reflux disease (GERD) * Peptic ulcer disease (gastric and duodenal ulcers) * Eradication of Helicobacter pylori infection (as part of combination therapy) * Prevention and treatment of NSAID-induced ulcers * ZollingerEllison syndrome * Stress ulcer prophylaxis in selected hospitalized patients * Upper gastrointestinal bleeding (after endoscopic therapy) Adult Dose * GERD: 20 mg orally once daily for 48 weeks

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Most patients find their target dose between 5 mg and 15 mg weekly, though some benefit from higher doses under medical supervision

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