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The medication helps to physically slow the digestive process, keeping food in the body for longer periods, and reducing the appetite while promoting feelings of fullness through hormone mimicry

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Tirzepatide was studied at up to 5 mg weekly

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Finally, there were differences in trial designs, patient characteristics, background therapy, and endpoint definitions

The primary objective of the study was to demonstrate that orforglipron is superior to placebo in body weight reduction from baseline after 72 weeks