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It varies by person
Hence, consulting a doctor before taking any supplement would be a wise decision
The only large study of healthy adults examining B12 supplement safety, using NHANES data, found no association between B12 supplementation and increased mortality at any dose, including 1,000 g/day or more (Wolffenbuttel, 2020)
The news around GLP-1s tends to read like a highlight reel
A B12 shot is more like a shot of a single alcoholic beverage, whereas an MIC B12 shot is a mixed drink or cocktail made up of various types of alcohol, sodas, and juices
certain allelic variants of several genes have been associated with an increased risk of essential hypertension, and almost all cases are known to be related to a familial history of hypertension (135)
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