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The development of dual GIPRGLP1R coagonists that bind to either one or the other receptor (sequence-mixed dual agonists) has emerged as an innovative therapeutic strategy for obesity and type 2 diabetes

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doi: 10.1007/s11356-014-3396-4 250 YadavS

The therapeutic potential of BAT activation has generated enormous pharmaceutical interest

Analogous to the BBB, the BRB has an inner component (iBRB) of retinal endothelial cells and an outer component (oBRB) formed by tight junctions between retinal pigment epithelial (RPE) cells [34]