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It dramatically amplifies and accelerates the underlying disease process

While its ability to influence multiple pathways of repair is supported by compelling preclinical data, the absence of high-quality human trials, the FDAs strict regulatory stance, and the risk of contamination from unregulated sources raise serious safety and legal concerns (including malpractice concerns and fines)

Animal studies on wound gels using 1-3% neem leaf extract found it sped up healing without causing irritation

Spinal-cord involvement in diabetic peripheral neuropathy

In moderation, hydrogen sulfide provides anti-inflammatory properties to the microbiota, boosts the immune system, and promotes tissue repair

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