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For instance, it has been recently observed that in prostate cancer patients, polymorphism in GSTM3-3 may contribute to resistance to hormonal therapy through oxidative stress 45

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CrossRef Inhibition of protein tyrosine phosphatase improves mitochondrial bioenergetics and dynamics, reduces oxidative stress, and enhances adipogenic differentiation potential in metabolically impaired progenitor stem cells Katarzyna Kornicka-Garbowska, Lynda Bourebaba, Michael Rcken, Krzysztof Marycz Cell Communication and Signaling.2021;[Epub] CrossRef microRNAs in Human Adipose Tissue Physiology and Dysfunction Alina Kurylowicz Cells.2021

For purification, a 5 ml StrepTrap HP (GE Healthcare) was equilibrated with at least five column volumes of lysis buffer

This step might involve acid-base catalysis by the active-site cysteinyl thiolate (which could explain an effect of the second cysteinyl residue), and/or the conserved lysine residue, yielding GS in analogy to glutathione transferases (Fig