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If the MVR becomes more severe, with more blood flowing the wrong way, the heart must work harder to pump sufficient oxygenated blood around the body and the upper chamber of the heart can become dilated due to increased pressure

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Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial

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While SarZ, MgrA, AbfR and OhrR share a conserved cysteine in the N-terminal DNA binding domain that can become sulfenylated, 547,549,551,553,556 the identity of the nonconserved resolving Cys, as well as the Cys pair for other cysteine-based regulators from the MarR family differ