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We found that patients receiving tirzepatide were significantly more likely to achieve clinically meaningful weight loss thresholds and experienced greater reductions in body weight over time, said Brianna Cartwright, MS, principal research analyst and lead for Truveta Research at Truveta

Real-world data suggests higher rates in patients with pre-existing GERD, suggesting baseline gastrointestinal sensitivity influences reflux risk

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[33:17] Andrew Huberman Okay

However, semaglutide slows gastric emptying and reduces appetite, which may compound digestive changes already present after cholecystectomy