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Lipotropic weight-loss aid

10.1038/s41387-021-00159-y 108

doi: 10.1038/ncomms10615 114 InoueDChewGLLiuBMichelBCPangalloJDAvinoARet al

For long-term storage, the lyophilised powder stays best at 20C

For a drug generating $5 billion annually, 180 days of exclusivity for a generic competitor means hundreds of millions in above-market returns, because during this window the market operates as a duopoly rather than falling immediately to fully competitive generic pricing

IGF-1 promotes fatty acid transport in muscle [162, 183, 193] and its inhibition causes severe consequences like insulin resistance and eventual diabetes [162]