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Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice

Brittle Nails: Nails that break easily or develop a spoon-like shape

Osteoporosis GLP-1 promotes osteoblast proliferation and differentiation while suppressing osteoclastogenesis via NF-B/MAPK inhibition and OPG/RANKL rebalancing

Based on data from the phase 2 clinical trial of retatrutide (NCT04881760), published in the New England Journal of Medicine in 2023, gastrointestinal adverse events were among the most frequently reported side effects across all dose groups

Mol Cell Biochem 481 , 14871499 (2026)

Ann N Y Acad Sci 887:1830