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Optimizing receptor affinity is intricate, since the optimal GIP: GLP-1 activity ratio differs across tissues and patient demographics

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It targets both GIP and GLP-1 receptors, which helps reduce food intake and improve insulin sensitivity

Ideally, future studies should fulfill the following conditions: (a) a multicenter and prospective design

The amount of lipid-peroxidation was determined using a TBARS Assay Kit (Cayman Chemical, Cat#10009055), per manufacturer instructions and absorbance was measured at a wavelength between 530540 nm using a plate reader

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