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Novel pharmacogenomic locus implicated in angiotensin-converting enzyme inhibitor-induced angioedema

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DPP4 activity in plasma and liver was absent from Dpp4 / on SLD and HFHC diet and reduced by 60% and 75% in Dpp4 hep/ mice compared with controls (Figure 3, B and C)

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doi: 10.1016/j.pbiomolbio.2013.10.001