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Model Inputs and Setting Treatment effects, parameter trajectories, costs and utility: Treatment effects (weight loss percentage, SBP, lipids, and glycemic status) were sourced from the STEP 6 trial (Japan/Korea cohort) and the broader STEP program

Weeks 1-2: 0.5 to 1 mg daily

In that study, tirzepatide was associated with greater average weight loss: People taking the highest dose lost an average of 20.2% of their body weight, compared with 13.7% for those taking semaglutide

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