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MRP1/GS-X pump ATPase expression: is this the explanation for the cytoprotection of the heart against oxidative stress-induced redox imbalance in comparison to skeletal muscle cells

The Journal of Laboratory and Clinical Medicine

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W.Van HiltenJ

Mutations in the gene encoding OCTN2, SLC22A5 , can impair fatty acid metabolism and lead to systemic primary carnitine deficiency (SPCD, OMIM 212140) 8 , an autosomal recessive disorder whose clinical manifestations include cardiomyopathy, hypoglycemia, chronic muscle weakness and liver dysfunction 9

doi: 10.3389/fimmu.2021.658354 65 Bilotta AJYC