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To assess how the L585 substitutions in human albumin affect FcRn binding, we performed surface plasmon resonance (SPR) experiments, where biotinylated human FcRn was captured on a streptavidin (SA)-coupled sensor chip before a single concentration of each albumin variant was injected over at pH 5.5 (Fig

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With respect to the previously mentioned study, this proof-of concept study has important methodological strengths residing in the availability of baseline and post-treatment hepatic biopsies

Then continue your regular weekly schedule from that new day