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Patients planning surgery should discuss tirzepatide with their healthcare team, though recent guidance from the American Society of Anesthesiologists indicates most patients can continue GLP-1 receptor agonists perioperatively, with modifications only for those at high risk of gastrointestinal complications

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In addition, without this prohibition, compounders could immediately begin making copies of any drug that FDA approves, undermining both the FDA approval process and the generic drug market

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Skinner R, Trujillo A, Ma X, Beierle EA