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This impairment of DNA synthesis affects the rapidly dividing cells of the bone marrow earlier than other cells, resulting in the production of large, immature, hemoglobin-poor red blood cells (macrocytosis), as well as effects on white blood cells, including abnormal (hypersegmented) neutrophils and reduced overall cell counts (pancytopenia)

That is a meaningfully weaker claim than the titles phrasing implies, and it is the claim the evidence actually supports

Evidence of clinical pathology abnormalities in people with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) from an analytic cross-sectional study

Niacinamide: A B vitamin that improves aging facial skin appearance, Pubmed

In addition, knockdown of PKM2 in astrocytes attenuated DRD2-induced Nrf2 activation and GSH biosynthesis (Fig

These approaches remain largely investigational and are not widely used in mainstream medicine