While more research is needed to confirm these findings, this growing body of evidence indicates that GLP-1 pathways may have protective effects in the digestive tract, beyond their traditional use in metabolic care
Acetylation and insulin resistance: a focus on metabolic and mitogenic cascades of insulin signaling
This isn't a theoretical concern
However, a recent prospective MRI report has shown that while upward displacement of the optic chiasm was common among LDSF astronauts, there was no correlation between this and the clinical manifestations of SANS
Meanwhile, their high protein content is satiating and supports muscle health while on GLP-1 medications
Whether it pays off in the populations not yet read out type 2 diabetes (TRIUMPH-2), sleep apnea (TRIUMPH-3), cardiovascular outcomes (TRIUMPH-CVOT) is the next set of questions