In particular, glycaemic control is considered a key target of treatments for T2D patients, with high glycated haemoglobin (HbA1c) levels associated with disease progression [12]
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FOLFOX is associated with the development of sinusoidal obstruction syndrome (SOS) and nodular regenerative hyperplasia (3)
RagulatorRag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids
Thus, the disruptions of the kidney-brain axis contribute to the high morbidity of neurological disorders, such as cognitive impairment in CKD (Yan et al., 2024)
Preliminary research suggests these medications may have modest anti-inflammatory effects in certain contexts, which differs fundamentally from immunosuppression