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It can result in greater and more durable weight loss and remission of obesity-related conditions like type 2 diabetes

However, it has been shown to be a cytotoxin, meaning it can result in cell damage or death

Some patients may experience numbness or lumpiness that can persist for four to six weeks or longer

For patients prioritising maximum weight reduction, tirzepatide (Mounjaro) is a reasonable first-line choice pending clinical assessment, contraindication screening, and tolerance of the dose titration

In particular, CD4 + T cell subsets can differentiate to produce a variety of pro-inflammatory cytokines and chemokines, which are involved in the pathogenesis of RA

Materials and methods A hairy root culture of A