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These letters concern a television show featuring Oprah Winfrey that aired in 2024, which contained false and misleading claims about Novo Nordisks Ozempic, Wegovy, and Victoza, and Eli Lillys Mounjaro and Zepbound products

The first study, PIONEER 5, is reviewed above

How Does Wegovy Work for Weight Loss

A study showed that individuals taking 1 mg and 2.4 mg injectable semaglutide over a 28-week timeframe lost 7% and 9.6% of their weight, respectively

There is no strong evidence to suggest Wegovy or Ozempic affects the efficacy of emergency contraception

The lower nausea and vomiting rates with tirzepatide compared to CagriSema suggest it may be easier to tolerate, particularly during the titration phase