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Possible mild side effects include headache, restlessness, or slight blood pressure fluctuations

DNA damage accumulation with age drives PARP hyperactivation, accelerating NAD+ depletion in a self-reinforcing cycle

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Sorafenib is a multikinase inhibitor that demonstrates effective treatment in advanced cancers such as renal cell carcinoma, hepatocellular carcinoma, and thyroid cancer [115]

However, in cases of correctable conditions - like varicoceles, blockages in the reproductive tract, or undescended testes - surgery may be recommended to help improve sperm quality