Tirzepatide, marketed as Zepbound for weight loss, activates two hormone pathways in your brain that regulate appetite and blood sugar
Improvement of Chronic Spontaneous Urticaria After Glucagon-Like Peptide 1 Receptor Agonist Therapy: Report of Two Cases
The ICB have said this should become available later in 2025
DOI: 10.1016/S2215-0366(26)00n014-3 Never miss a breakthrough: Join the SciTechDaily newsletter
Wegovy (semaglutide injection, Novo Nordisk), Zepbound (tirzepatide injection, Eli Lilly), Saxenda (liraglutide injection, Novo Nordisk), and oral Wegovy (semaglutide tablets, approved December 2025)
(Note: Your provider will determine the dose thats appropriate for your needs.) Side effects Commonly reported side effects of this medication include: Temporary blurred vision Paresthesia (burning, prickling, or tingling sensations) Speech or language problems Drowsiness Memory problems Loss of appetite Generalized slowing of mental and physical activity Nervousness Dry mouth Fatigue Serious side effects include: Feeling sad or empty Dizziness Eye redness or pain Increased eye pressure Menstrual changes or pain Kidney stones Trouble concentrating or paying attention Unusual tiredness or weakness Please contact your provider right away if you experience: Change in vision or eye pain Flank pain Dark urine or blood in the urine Severe stomach or stomach pain that lasts more than a few days Changes in mood or behavior Suicidal thoughts Dizziness or loss of muscle coordination Trouble thinking clearly Increased fatigue Faintness Skin rash Changes in menstrual cycle or breakthrough bleeding Black Box Warning Precautions Before using topiramate, tell your health care provider about your medical history, especially if you have glaucoma or eye problems, kidney problems (such as kidney stones), liver problems, depression or thoughts of suicide, lung or breathing problems, metabolic acidosis, high blood ammonia levels, long-term diarrhea, low body temperature, a diet high in fat and low in carbohydrates (like a ketogenic diet), or soft or brittle bones
