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"When you lose weight, you're not only losing fat," Codorniz says

Morris, G., et al., The Glutathione System: A New Drug Target in Neuroimmune Disorders

Am J Clin Nutr (1995) 61(2):296302

But they're also unlikely to have contributed meaningfully to any weight loss you've experienced

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For semaglutide-related constipation, longer-term use may be appropriate under clinician guidance