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Biochim Biophys Acta 1830:32173266

The results showed a significant increase in skin density and thickness, with a 67% reduction in wrinkle volume and improved elasticity, as measured by ultrasound and profilometry (Leyden et al., 2002)

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5 times a week 2, 8, or 14 months Pepsin activity and to- tal proteolytic activity [82] Intramus- cular injec- tion 7 g/kg 7 days Kidney enzyme activity [102] Intraperito- neal injec- tion 7 g/kg 7 days Kidney functionality after cis-platin-induced kidney failure [103] 2.5