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Mechanism of Action: 2 adrenoreceptor agonist Peripheral : 2 agonists can directly cause arterial vasoconstriction , which can cause an initial phase of hypertension , before centrally mediated effects predominate, resulting in reduced sympathetic outflow from the CNS, which results in both bradycardia and hypotension (Malayala et al, 2022

R., Johansson, E., Fulle, S., Skyggebjerg, R

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In metabolic disorders, such as metabolic dysfunction-associated steatotic liver disease (MASLD), ferroptosis exacerbates lipid oxidation and contributes to tissue damage [91]

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