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Retatrutide contribution includes improved insulin sensitivity (GLP-1 and GIP), reduced liver fat (glucagon), improved lipid profiles (all three receptors), and reduced blood pressure (weight loss effect)

Patients are better able to stick to a reduced-calorie diet due to taking this medication

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Coverage, availability, expected out-of-pocket cost, prior authorization requirements, and the ability to maintain treatment should be reviewed before choosing a medication

Semaglutide belongs to a class of drugs called GLP-1 agonists

The drug helps people lose weight but doesn't directly cause weight loss