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For both, the temptation in midlife is to add more products

Expression and splicing of the insulin-like growth factor gene in rodent muscle is associated with muscle satellite (stem) cell activation following local tissue damage

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Anderson JL, Muhlestein JB, Horne BD, Carlquist JF, Bair TL, Madsen TE, and Pearson RR (2000)

Most strikingly, multiple trials have now shown that GLP-1 agonists can lead to the resolution of MASH, a severe form of fatty liver disease, without worsening of liver fibrosis, which is a common adverse outcome seen with some current medications