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GLP-1 and GIP/GLP-1 RAs Pipeline Source: clinicaltrials.gov Value Differentiation and Connection to Coverage New entrants to this crowded market will need to differentiate themselves through a strong payer value story that spans beyond T2D, overweight/obesity, CVD indications

This combo works on two fronts accelerating fat breakdown and stimulating regenerative repair making it ideal for those who want to burn fat without compromising energy or muscle mass

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Fischer, Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

Increased GIP levels are observed in obesity, as fat is a potent stimulus of GIP secretion