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Additionally, research supports the notion that lifestylebased interventions resulting in a weight reduction of at least 5% over one year can produce histological steatosis improvement

This is vital for organs with high energy demands like the heart and muscles

These molecules can increase insulin release and satiety, interesting effects that could also be useful in the treatment of domestic animals pathologies, however their use in veterinary medicine are still limited

Ideally, this should be complemented by other lifestyle, such as increased physical activity and behavior modifications [228]

To compare serum metabolites across different ages in mice, we compared the metabolites at 4, 14, and 21 months of age against those at 2 months of age, calculating the fold changes relative to the 2-month-old group

IUBMB Life 74 , 5361 (2022)